Vol. 8, Special Issue 5 (2020)
Tramadol and Butorphanol in post-surgical pain management in canine
Author(s): Sarkiri Engti, Parsha Jyoti Nath, Kushal Konwar Sarma, Nikhil Ch. Nath and Jadav Sarma
Abstract: The present study was undertaken to evaluate the analgesic efficacy of Butorphanol and Tramadol as post-surgical analgesics in eighteen ovariohysterectomy bitches, divided into three groups’ containing 6 animals in each. Group A and Group B were administered with Butorphanol @ 0.35 mg/kg IM and Tramadol @ 1.5 mg/kg IM respectively as single dose immediately after completion of operation and the animals of Group C were kept as control without any post-operative analgesic in entire observation period. The physiological parameters and pain assessment test were taken pre and postoperatively at 0 min, 15 min, 30 min, 1 hr, 2 hrs, 4 hrs and 6 hrs. The physiological parameters viz. heart rate, pulse rate, respiration rate, rectal temperature and Oxygen saturation (SpO2) showed significant (p<0.01) variation between the groups but these variations were noted within physiological reference range. The Mean Arterial Pressure (MAP) did not show any significant variation between the groups or between time intervals in all the groups. The pain assessment test done by using University of Melbourne Pain Scale (UMPS) showed significantly (p<0.01) increased score in the post-operative period in Group C compared to Groups A and B; while in Groups A and B the pain scores remains relatively static till 4 hours after a initial rise in post-operative periods. Comparison between Group A and Group B, the scores were increased significantly from 4 hrs till 6 hrs post operation in Group A. Based on the present study, it was found that degree of analgesia was better with Butorphanol while duration of analgesia was longer with Tramadol. Both the synthetic opioids were found to be economic and effective in alleviation of post-operative pain in dogs.
DOI: 10.22271/chemi.2020.v8.i5c.10495
Pages: 151-153 | 629 Views 58 Downloads
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How to cite this article:
Sarkiri Engti, Parsha Jyoti Nath, Kushal Konwar Sarma, Nikhil Ch. Nath and Jadav Sarma. Tramadol and Butorphanol in post-surgical pain management in canine. International Journal of Chemical Studies. 2020; 8(5): 151-153. DOI: 10.22271/chemi.2020.v8.i5c.10495
