Vol. 13, Issue 2 (2025)
Microwave-Assisted synthesis and characterization of bis-benzodiazepine derivatives
Author(s): Sandip Patole
Abstract: A new and efficient method using microwave assistance has been created for making innovative bis-benzodiazepine derivatives, which are a type of seven-membered heterocyclic compounds that hold significant interest in the pharmaceutical world. The process began with N-phenyl-substituted succinimide chalcone as the main precursor, resulting in a variety of bis-benzodiazepine derivatives (2a-d). This microwave-assisted technique has several advantages over traditional methods, such as shorter reaction times, better yields, and greater ease of operation. The structures of the compounds we synthesized were clearly confirmed through detailed spectral analysis, including FT-IR, 1HNMR, 13CNMR, and mass spectrometry. This innovative and quick approach highlights the power of microwave irradiation in creating complex heterocyclic systems and offers a promising pathway for developing biologically significant benzodiazepine derivatives.
DOI: 10.22271/chemi.2025.v13.i2a.12637
Pages: 104-106 | 72 Views 39 Downloads
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How to cite this article:
Sandip Patole. Microwave-Assisted synthesis and characterization of bis-benzodiazepine derivatives. Int J Chem Stud 2025;13(2):104-106. DOI: 10.22271/chemi.2025.v13.i2a.12637
