Vol. 13, Issue 1 (2025)
Acyl pyrazole and hydrazone derived schiff base and their moo2 (VI) complex: synthesis, characterization, molecular structural investigations, and insilico biological evaluations
Author(s): MK Parte, PK Vishwakarma and RC Maurya
Abstract: This research presents the synthesis of the ligand (1Z, N'E)-N'-(cyclohexyl (5-hydroxy-3-methyl-1-phenyl-4, 5-dihydro-1H-pyrazol-4-yl) methylene)-2-hydroxybenzohydrazonic acid (H3L) and its complex, cis-[MoO2 (HL) (Me OH)] [C1]. The physicochemical, spectral, and electrochemical evaluations suggested the molecular formula of the complex. DFT-based geometrical computations clarified the molecular structure of the compound. It was found that the ligand coordinates through the azomethine nitrogen and two enolic oxygen of the Schiff base moiety, maintaining a 1:1 ratio with the metal. Furthermore, the title compounds exhibited bioactivity scores and drug-likeness as determined by Molinspiration software, along with ADME properties that suggest potential pharmacological activity.
Pages: 03-12 | 81 Views 44 Downloads
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How to cite this article:
MK Parte, PK Vishwakarma, RC Maurya. Acyl pyrazole and hydrazone derived schiff base and their moo2 (VI) complex: synthesis, characterization, molecular structural investigations, and insilico biological evaluations. Int J Chem Stud 2025;13(1):03-12.
