Vol. 12, Issue 4 (2024)
In silico evaluation of flavonoids from Citrus sinensis as inhibitors of HIV-1 reverse transcriptase
Author(s): SY Mane
Abstract: The present study predicts the binding affinities and inhibitory potential of flavonoids from Citrus sinensis (sweet orange) against HIV - 1 reverse transcriptase a key enzyme in HIV replication studied computationally using molecular docking. The standard ligand i.e. inhibitor drug molecule 11-cyclopropyl-5,11-dihydro-4-methyl-6h-dipyrido[3,2-b:2',3'-e] [1,4] diazepin-6-one (NVP) act as standard ligand and redock with protein. The redocking score of NVP is compared with the docking score of other ligands obtained from the Citrus sinensis.
Pages: 141-144 | 143 Views 74 Downloads
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How to cite this article:
SY Mane. In silico evaluation of flavonoids from Citrus sinensis as inhibitors of HIV-1 reverse transcriptase. Int J Chem Stud 2024;12(4):141-144.
