Vol. 12, Issue 4 (2024)
Understanding the link between diabetes mellitus and fatty liver disease: A narrative review
Author(s): Azher adnan, Zainab Mohammed Farhan and Osama A Mohsein
Abstract: Non-alcoholic fatty liver disease (NAFLD) is very common in people with type 2 diabetes mellitus (T2DM). This is probably because people with T2DM are often overweight and have trouble using insulin. People with type 1 diabetes (T1DM) can also have NAFLD, but it is important to tell the difference between the two. Glycogen hepatopathy is more common in people with T1DM and can cause hepatomegaly and problems with liver function. People with diabetes who are overweight or fat can avoid or treat NAFLD by losing weight through diet and exercise. People with T2DM who have NAFLD can also get better with bariatric surgery. New weight loss drugs should also be studied to see how they affect the growth and spread of NAFLD. A few studies show that statins and some drugs used to treat T2DM (such as TZDs, GLP-1 analogs, and DPP-4) inhibitors) may help diabetes people avoid or treat NAFLD. Type 2 Diabetes Mellitus (T2DM) and Nonalcoholic Fatty Liver Disease (NAFLD) are spreading quickly around the world. Soon, they will be found in every country. There is a link between them because of metabolic risk factors like being overweight, having insulin resistance (IR), and living a poor life. It increases the chance of both liver and heart problems. Some patients feel bad about using the term "NAFLD," but not all of them do. Soon, a more useful one will be released. Medical treatments can work on both diseases at the same time because their main pathophysiological process is the same. Lifestyle changes, drug choices (as more molecules designed for treating T2DM may also help with NAFLD), and surgery are some of the strategies that can be used. This review is mostly about how NAFLD and T2DM can happen together, such as how to use the right words, how common it is, and how many diabetics die from it. To sum up, we've talked about the main pathophysiological processes, the risk stratification method for NAFLD and nonalcoholic steatohepatitis (NASH), and the tools that are used to measure fibrosis. Last but not least, we looked at the different ways that NAFLD linked to T2DM can be treated right now.
Pages: 40-48 | 170 Views 65 Downloads
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How to cite this article:
Azher adnan, Zainab Mohammed Farhan, Osama A Mohsein. Understanding the link between diabetes mellitus and fatty liver disease: A narrative review. Int J Chem Stud 2024;12(4):40-48.
