Vol. 11, Issue 6 (2023)
Synthesis and biological investigation of novel heterocyclic thiosemicarbazone silver (I) complexes as potent antimicrobial agents
Author(s): Elvan Hasanoğlu Özkan, Nurdan Kurnaz Yetim, Hatice Öğütcü and Dilek Nartop
Abstract:
Herein, new heterocyclic thiosemicarbazone silver (I) complexes (Tsc1, Tsc2, Tsc3, Tsc4) were synthesized by the template method, and their structures were determined using some spectral techniques: element analysis, Fourier transform infrared spectra (FT-IR), proton nuclear magnetic resonance (1H-NMR), thermogravimetric analysis (TG-DTA), organic elemental analysis, and magnetic susceptibility measurements. The biological activities of the newly synthesized heterocyclic thiosemicarbazone silver (I) complexes were investigated as potent antimicrobial agents against some disease-causing pathogens. For this purpose, the well-diffusion method was used. The biological activity results demonstrated that all novel heterocyclic thiosemicarbazone silver (I) complexes have high or moderate inhibitory activity of the tested pathogenic strains.
Graphical Abstract
DOI: 10.22271/chemi.2023.v11.i6a.12367
Pages: 35-41 | 286 Views 136 Downloads
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How to cite this article:
Elvan Hasanoğlu Özkan, Nurdan Kurnaz Yetim, Hatice Öğütcü, Dilek Nartop. Synthesis and biological investigation of novel heterocyclic thiosemicarbazone silver (I) complexes as potent antimicrobial agents. Int J Chem Stud 2023;11(6):35-41. DOI: 10.22271/chemi.2023.v11.i6a.12367
