Vol. 10, Issue 1 (2022)
Adaptogenic potential of Poorna Chandrodayam Chendooram (PCM-Metallic Drug) on free radical and antioxidants levels in brain, liver and kidney of rats
Author(s): Muthukumaran Pakkirisamy, Pattabiraman K and Vava Mohaideen Hazeena Begum
Abstract: We evaluated the Adaptogenic potential of Poorna Chandrodayam Chendooram (PCC - Metallic Drug) on Free radicals, Antioxidative and Metallothionein (MT) status in Brain, Liver and Kidney of Normal rats compared to Drug Treated rats. The concentrations of Lipid Peroxidation (LPO), Protein carbonyls (PCO), activities of Xantione oxidase (XO), Superoxide dismutase (SOD), Catalase (CAT), glutathione peroxidase (GPx), Glutathione (GSH), vitamin C and vitamin E and Metallothionein (MT) were used as biomarkers. In the Brain, Liver and Kidney of young animals, enhanced oxidative stress was accompanied by compromised antioxidant defenses. Administration of Poorna Chandrodayam Chendooram (PCC - Metallic Drug) effectively modulated oxidative stress and enhanced antioxidant status in the Brain, Liver and Kidney of rats. The results of the present study demonstrate that Poorna Chandrodayam Chendooram (PCC - Metallic Drug) inhibits the Free radicals and increased antioxidant, Metallothionine which might be due to bioactive compound present in the Drug.
Pages: 163-169 | 408 Views 167 Downloads
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How to cite this article:
Muthukumaran Pakkirisamy, Pattabiraman K, Vava Mohaideen Hazeena Begum. Adaptogenic potential of Poorna Chandrodayam Chendooram (PCM-Metallic Drug) on free radical and antioxidants levels in brain, liver and kidney of rats. Int J Chem Stud 2022;10(1):163-169.
