International Journal of Chemical Studies
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P-ISSN: 2349-8528, E-ISSN: 2321-4902   |   Impact Factor: GIF: 0.565

International Journal of Chemical Studies

Vol. 9, Issue 1 (2021)
Electron-transfer oxidation of Organo-cuprates with Benzophenone: Synthesis of Biaryls


Author(s): M Jalilur Rahman, Md. Abdul Malek, Rehana Pervin and Shameem Ara Begum

Abstract: A mild and simple way to synthesize Biaryls from aryl bromides via formation of organo-cuprate complexes has been developed. The Organo-cuprates {Ar2CuMgBr.Mg(I)Br}, generated from Arylmagnesium bromide and half equivalent of copper(I) iodide in dry THF at lower temperature under nitrogen, underwent electron-transfer oxidation with an aryl ketone benzophenone producing homo-coupled Biaryls in moderate yields. Aryl bromides either with electron-donating or with electron-withdrawing substituents were smoothly transformed into the corresponding Biaryls through formation of aryl Grignard reagents and Organo-cuprate complexes in a one pot reaction under this electron-transfer oxidation procedure.

DOI: 10.22271/chemi.2021.v9.i1a.11596

Pages: 41-44  |  429 Views  26 Downloads

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How to cite this article:
M Jalilur Rahman, Md. Abdul Malek, Rehana Pervin, Shameem Ara Begum. Electron-transfer oxidation of Organo-cuprates with Benzophenone: Synthesis of Biaryls. Int J Chem Stud 2021;9(1):41-44. DOI: 10.22271/chemi.2021.v9.i1a.11596
International Journal of Chemical Studies