International Journal of Chemical Studies
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P-ISSN: 2349-8528, E-ISSN: 2321-4902   |   Impact Factor: GIF: 0.565

International Journal of Chemical Studies

Vol. 9, Issue 1 (2021)
Phytochemical analysis and antimicrobial activity of Aframomum chrysanthum seed extracts


Author(s): Gloria Ihuoma Ndukwe, Oshiozuwenose Irekhafe Iyemeaikere and Joshua Lelesi Konne

Abstract: Three extracts of Aframomum chrysanthum seeds were investigated for antimicrobial activity using disc diffusion method. Varied concentration-dependent antimicrobial activities were exhibited by n-hexane and ethylacetate extracts against the investigated pathogenic microorganisms especially Staphylococcus aureus. Susceptibility testing conducted on all the extracts showed that n-hexane extract had moderate antimicrobial activity at 200 mg/ml against Staphylococcus aureus, Candida albicans and Trichophyton rubrum. All the isolates were observed to be resistant to the methanol extract. n-Hexane extract displayed potent antimicrobial activity against Trichophyton rubrum when compared to the standard antifungal drug (fungisol) used in the investigation. Phytochemical analysis carried out on the n-hexane extract of Aframomum chrysanthum seed, revealed the presence of eighty-one (81) compounds made up of phytosterols, alkaloids, anthraquinone, phospholipids and fatty acids. The presence of these phytochemicals is an indication that the plant could be used as antimicrobial agent.

DOI: 10.22271/chemi.2021.v9.i1a.11447

Pages: 14-20  |  483 Views  37 Downloads

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How to cite this article:
Gloria Ihuoma Ndukwe, Oshiozuwenose Irekhafe Iyemeaikere, Joshua Lelesi Konne. Phytochemical analysis and antimicrobial activity of Aframomum chrysanthum seed extracts. Int J Chem Stud 2021;9(1):14-20. DOI: 10.22271/chemi.2021.v9.i1a.11447
International Journal of Chemical Studies