Vol. 7, Issue 6 (2019)
High level of antimicrobial-resistant pathogenic Escherichia coli in diarrheic goats reared under semi-intensive system of management at University farm, Maharashtra
Author(s): Mahendra Mohan Yadav
Abstract: Multiple Antibiotic resistances in Escherichia coli are of particular concern for the reason that it is the most common Gram-negative pathogen associated with diarrhea in livestock. Hence, a clinical investigation was conducted with the objective to determine the in vitro virulence antibiotic sensitivity pattern of E. coli isolated from diarrheic goats maintained at All India Co-ordinated Research Project (AICRP) on Osmanabadi Goats, Mahatma Phule Krishi Vidyapeeth (MPKV), Rahuri Maharashtra State. From 54 diarrheic goats, Escherichia coli were isolated from 41 samples. In vitro virulence assay indicates that all the 41 E. coli isolates were positive for hemolysin assay and congo red test. Antibiotic sensitivity pattern for 14 routinely used antibiotics revealed that highest resistance was observed in Ampicillin (AMP), Amoxycillin / Clavulanic acid (AMC), Penicillin (P) (100.0% each), followed by Ceftriaxone (CTR) and Co-trimoxazole (Co) and Tetracycline (87.80% each) Cefotaxime (CTX) (85.37%), Cefoperazone (CPZ) (82.93%), and Ciprofloxacin (CP) (78.05%), Cefachlor (CF) (73.17%), Gentamicin (G) (60.98%), Chloramphenicol (C) (29.27%). While the least antimicrobial resistance was observed in Enrofloxacin (Ex) (19.51%) followed by Levofloxacin (LE) (14.63%). Multiple antimicrobial resistances ranging from 5 to 13 antimicrobials were observed in all the 41 isolates. Seven major antimicrobial resistance patterns were observed involving 15 to 41 isolates. Thirty isolates were showing resistance to minimum 10 antimicrobials. Multidrug resistant strains together with virulent character of E. coli are a matter of great concern as resistance genes are easily transferable to other strains with potential to cause a disease. Multidrug resistant virulent E. coli strains in goats’ warrants a nearly possible transmission in human population.
Pages: 62-67 | 564 Views 63 Downloads
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How to cite this article:
Mahendra Mohan Yadav. High level of antimicrobial-resistant pathogenic Escherichia coli in diarrheic goats reared under semi-intensive system of management at University farm, Maharashtra. Int J Chem Stud 2019;7(6):62-67.
