Vol. 7, Issue 3 (2019)
Preparation and characterization of PCL-TCP scaffolds with solvent casting and particulate leaching method
Author(s): Kale VD, Ravi Sundar George, A Arun Prasad, Ganne Venkata Sudhakar Rao, TA Kannan and H Pushkin Raj
Abstract: Polycaprolactone and beta tricalcium phosphate scaffolds were successfully fabricated by solvent casting and particulate leaching method. The scaffolds had suitable pore sizes, which were very important for cell penetration, adhesion, and spreading. Porogen size had an impact on the scaffold morphology and the porosity. PCL-TCP scaffold increased the wettability or hydrophilicity of the scaffold. Adipose derived mesenchymal stem cells were viable, attached to the scaffold and migrated into the pores of the scaffold on day 14th & 28th. X-ray diffraction spectra showed several peaks which corresponds to the beta tricalcium phosphate. These peaks confirmed the presence of beta tricalcium phosphate in the scaffold.
Pages: 4468-4471 | 613 Views 278 Downloads
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How to cite this article:
Kale VD, Ravi Sundar George, A Arun Prasad, Ganne Venkata Sudhakar Rao, TA Kannan, H Pushkin Raj. Preparation and characterization of PCL-TCP scaffolds with solvent casting and particulate leaching method. Int J Chem Stud 2019;7(3):4468-4471.
