International Journal of Chemical Studies
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P-ISSN: 2349-8528, E-ISSN: 2321-4902   |   

Vol. 7, Issue 3 (2019)

Formulation of sweet flag oil (Acorus calamus) nanoemulsion by spontaneous emulsification method for the management of Sitophilus oryzae


Author(s): V Dhivya, S Jeyarajan Nelson, KS Subramanian, YS Johnson Thangaraj Edward, K Rajamani, VP Santhanakrishnan and S Sithanantham

Abstract: Sweet flag (Acorus calamus L.) O/W nanoemulsion was formulated by the spontaneous emulsification method. The emulsion was formulated using sweet flag oil (6%), non-ionic surfactant with Hydrophile-Lipophile Balance (HLB) value-10.0 and cyclohexane as solvent. The emulsion was formulated with the different ration of oil and surfactant, 1:0.5, 1:1, 1:1.5 and 1:2. The minimum droplet size 17.9 nm was recorded in 1:2 (v/v) of oil and surfactant. The droplet diameter decreased with an increase in the surfactant concentration. The scanning electron microscope (SEM) image revealed that droplets were spherical in shape. The developed formulations were evaluated for insecticidal action against Sitophilus oryzae. The insecticidal action increased with an increase in surfactant concentration and dose. The median lethal concentration (LC50) value was 0.51% for 1:2 ratio formulation while it was 2.35% for 1:0.5 ratio formulation. The LC50 value decreased with decrease in droplet size and increase in surfactant concentration.

Pages: 2072-2076  |  656 Views  196 Downloads

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How to cite this article:
V Dhivya, S Jeyarajan Nelson, KS Subramanian, YS Johnson Thangaraj Edward, K Rajamani, VP Santhanakrishnan, S Sithanantham. Formulation of sweet flag oil (Acorus calamus) nanoemulsion by spontaneous emulsification method for the management of Sitophilus oryzae. Int J Chem Stud 2019;7(3):2072-2076.
 

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