Vol. 7, Issue 1 (2019)
Canine N-terminal-pro brain natriuretic peptides (NT-proBNP): A promising marker of heart failure
Author(s): P Thirunavukkarasu, Dr. B Nagarajan, Dr. K Vijayarani and Dr. K Kumanan
Abstract: Acquired heart diseases (AHD) are common and often fatal when it leads to CHF in dogs and it occurs most often secondary to degenerative mitral valve disease (MVD), dilated cardiomyopathy (DCM), pericardial diseases and Hypertrophic cardiomyopathy (HCM). Early recognition of AHD is of clinical importance. Animals with acquired heart diseases were selected from the animals that were brought to MVC teaching hospital and they were grouped as following apparently healthy dogs (Control group), Dilated Cardiomyopathy (DCM), Mitral Valve Disease (MVD), Pericardial diseases, Hypertrophic Cardiomyopathy (HCM). NT-proBNP Assay was conducted in the control and clinical group. In NT-proBNP assay highly significant increase in levels was observed in Dilated Cardiomyopathy, MVD with systolic failure, MVD without systolic failure and even in occult cardiac diseases, which indicated that this marker is highly sensitive and specific in cardiac diseases. The cardiac biomarker NT-proBNP was very effective and specific marker and very useful in diagnosing and categorizing the cardiac diseases in dogs.
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Pages: 718-719 | 625 Views 142 Downloads
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How to cite this article:
P Thirunavukkarasu, Dr. B Nagarajan, Dr. K Vijayarani, Dr. K Kumanan. Canine N-terminal-pro brain natriuretic peptides (NT-proBNP): A promising marker of heart failure. Int J Chem Stud 2019;7(1):718-719.
