Vol. 6, Issue 2 (2018)
Phytochemical screening, Antioxidant, Anti-inflammatory and Anti microbial activities of Aegle marmelos leaf extracts
Author(s): PN Timbadiya, MK Mandavia and BA Golakiya
Abstract: This study was performed to investigate the phytochemical screening, physicochemical activities, oxidative enzyme activities, anti microbial, antioxidant as well as anti-inflammatory properties from Aegle marmelos leaf different extracts. This investigation was achieved by extraction of medicinal plants in different solvents (Hexane, Chloroform, Methanol, water and 90% Methanol), preliminary phytochemical and physicochemical screening, oxidative enzyme activity, antimicrobial activity, antioxidant activity, antidiabetic activity, separation and identification of phytochemicals having antidiabetic activity from bioactive extracts. Results revels Aegle marmelos leaf all polar extracts had highest phytochemicals. The plant leaves rich in flavanoids 63.64±0.45 and phenol 53.45±0.39. The plant leaf powder contained the high level of calcium51861.81ppm, magnesium1713.01ppm and Iron 161.08. Different extracts of Aegle maemelos – leaf inhibited the growth of all four bacteria Bacillus subtilis, Bacillus cereus, Bacillus megaterium and Escherichia coli except hexane and chloroform extracts which had not showed activity against Bacillus subtilis. Antifungal activity was not found in plants extract against Alterneria. Highest activity was found against Fussariumoxispora, Aspergillus parasiticus followed by Aspergillus flavus. All five extracts of Aegle maemelos – leaf inhibited the growth of Fussariumoxispora. Only hexane, water and 90% methanol extracts inhibited the growth of Aspergillus parasiticus, while water and 90% methanol extractsinhibited the growth of Aspergillus flavus. It was observed that the extracts of Aegle marmelos (Beal) leaf had higher DPPH scavenging activity in methanol extract than that of the other extracts 79.52 ± 0.35%. The inhibition of albumin denaturation exerted by Aegle marmelos (Beal) leaf had higher activity in methanol extract than that of the other extracts 65.30±1.07%.
Pages: 3509-3517 | 547 Views 37 Downloads
How to cite this article:
PN Timbadiya, MK Mandavia, BA Golakiya. Phytochemical screening, Antioxidant, Anti-inflammatory and Anti microbial activities of Aegle marmelos leaf extracts. Int J Chem Stud 2018;6(2):3509-3517.