Vol. 6, Issue 2 (2018)
Chemometric approach to evaluate catalytic activity of [CTAB/ 18-Crown-6]: A binary catalytic system for one pot green synthesis of 4-benzylidene-3-methylisoxazol-5(4H)-one derivatives at room temperature
Author(s): Deepali Agarwal, Ankita Verma, Jyotsna Dhanik and Virendra Kumar Kasana
Abstract: A highly efficient binary catalytic system [CTAB/ 18-Crown-6] has been developed for one pot three component green synthesis of 4-benzylidene-3-methylisoxazol-5(4H)-one derivatives by reaction of aromatic aldehydes, ethyl acetoacetate and hydroxylamine hydrochloride. Catalytic productivity of [CTAB/ 18-Crown-6] has been studied using different ratio combination of cetyltrimethylammonium bromide (CTAB) and 18-Crown-6 in varying water: ethanol ratio. Percent yield of isoxazol-5(4H)-ones obtained by different [CTAB/ 18-Crown-6] ratio in variable water: ethanol solution were analyzed by descriptive statistical analysis and variable correlation analysis to evaluate the catalytic efficacy of binary [CTAB/ 18-Crown-6] system.
Pages: 3003-3007 | 757 Views 136 Downloads
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How to cite this article:
Deepali Agarwal, Ankita Verma, Jyotsna Dhanik, Virendra Kumar Kasana. Chemometric approach to evaluate catalytic activity of [CTAB/ 18-Crown-6]: A binary catalytic system for one pot green synthesis of 4-benzylidene-3-methylisoxazol-5(4H)-one derivatives at room temperature. Int J Chem Stud 2018;6(2):3003-3007.
