International Journal of Chemical Studies
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P-ISSN: 2349-8528, E-ISSN: 2321-4902   |   Impact Factor: GIF: 0.565 NAAS Rating: 5.31 NEW

International Journal of Chemical Studies

Vol. 6, Issue 2 (2018)
Chemometric approach to evaluate catalytic activity of [CTAB/ 18-Crown-6]: A binary catalytic system for one pot green synthesis of 4-benzylidene-3-methylisoxazol-5(4H)-one derivatives at room temperature


Author(s): Deepali Agarwal, Ankita Verma, Jyotsna Dhanik and Virendra Kumar Kasana

Abstract: A highly efficient binary catalytic system [CTAB/ 18-Crown-6] has been developed for one pot three component green synthesis of 4-benzylidene-3-methylisoxazol-5(4H)-one derivatives by reaction of aromatic aldehydes, ethyl acetoacetate and hydroxylamine hydrochloride. Catalytic productivity of [CTAB/ 18-Crown-6] has been studied using different ratio combination of cetyltrimethylammonium bromide (CTAB) and 18-Crown-6 in varying water: ethanol ratio. Percent yield of isoxazol-5(4H)-ones obtained by different [CTAB/ 18-Crown-6] ratio in variable water: ethanol solution were analyzed by descriptive statistical analysis and variable correlation analysis to evaluate the catalytic efficacy of binary [CTAB/ 18-Crown-6] system.

Pages: 3003-3007  |  286 Views  9 Downloads

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How to cite this article:
Deepali Agarwal, Ankita Verma, Jyotsna Dhanik, Virendra Kumar Kasana. Chemometric approach to evaluate catalytic activity of [CTAB/ 18-Crown-6]: A binary catalytic system for one pot green synthesis of 4-benzylidene-3-methylisoxazol-5(4H)-one derivatives at room temperature. Int J Chem Stud 2018;6(2):3003-3007.
International Journal of Chemical Studies