International Journal of Chemical Studies
Vol. 6, Issue 1 (2018)
Serum biochemical changes in ochratoxin induced toxicity and its amelioration using diatomacious earth in broiler chicken
Author(s): VP Anand, AW Lakkawar, HD Narayanaswamy and ML Sathyanarayana
Abstract: The ability of Diatomaceous earth (DAE) in reducing the toxic effects of ochratoxin (OTA) in broiler diet was evaluated. DAE was supplemented @ 400 and 800 mg kg-1 of feed along with 0.5 and 1 ppm of OTA/kg of feed. Healthy unsexed day-old broiler chicks (n=360) were assigned to 9 groups comprising of control and treatment groups. Feeding of OTA resulted in significantly lower feed intake as well as body weight gain and increase in feed conversion ratio in comparison to the control groups. Supplementation of DAE in ochratoxin mixed diet significantly reduced the deleterious effects of OTA on growth parameters. Feeding of OTA alone caused significant decrease in serum levels of total proteins, albumin, triglycerides and cholesterol. However, significant increase was found in serum levels of AST, ALT, ALP, BUN and creatinine in OTA fed broilers. Supplementation of DAE to the OTA mixed feed ameliorated the adverse effect of ochratoxin on the serum biochemical values by causing increase in serum total proteins, albumin, triglycerides and cholesterol levels. In addition, a significant increase was recorded in AST, ALT, ALP, BUN and creatinine levels in DAE supplemented broilers. The study concluded that diatomaceous earth is an effective adsorbent to decrease the toxic adverse effects of ochratoxin in broiler chicken.
Pages: 673-679 | 393 Views 6 Downloads
How to cite this article:
VP Anand, AW Lakkawar, HD Narayanaswamy, ML Sathyanarayana. Serum biochemical changes in ochratoxin induced toxicity and its amelioration using diatomacious earth in broiler chicken. Int J Chem Stud 2018;6(1):673-679.