International Journal of Chemical Studies
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P-ISSN: 2349-8528, E-ISSN: 2321-4902   |   Impact Factor: GIF: 0.565 NAAS Rating: 5.31 NEW

International Journal of Chemical Studies

Vol. 5, Issue 3 (2017)
Tetrabutylammonium prolinate: A catalytic moiety for the synthesis of one pot five component synthesis of octahydroquinazolinone-1,3-dicarbaldehyde derivatives


Author(s): Shivani Verma and Virendra Kasana

Abstract: A series of novel derivatives of quinazolinone have been synthesized in one pot by reacting of substituted benzaldehyde, dimedone, urea/thiourea and formic acid at room temperature catalyzed by tetrabutylammonium prolinate (5mol%) as an efficient, environmentally benign and eco-friendly catalyst with excellent yield (82-93%), easy work up and short reaction time. The synthesized derivatives of octahydroquinazolinone-1,3,-dicarbaldehyde characterized and confirmed by 1HNMR and 13CNMR data.

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How to cite this article:
Shivani Verma, Virendra Kasana. Tetrabutylammonium prolinate: A catalytic moiety for the synthesis of one pot five component synthesis of octahydroquinazolinone-1,3-dicarbaldehyde derivatives. Int J Chem Stud 2017;5(3):708-718.
International Journal of Chemical Studies