International Journal of Chemical Studies
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P-ISSN: 2349-8528, E-ISSN: 2321-4902   |   Impact Factor: GIF: 0.565 NAAS Rating: 5.31 NEW

International Journal of Chemical Studies

Vol. 5, Issue 3 (2017)
Synthesis and antibacterial screening of some novel cinnamic acid derivatives


Author(s): Amrita Parle and Tejpal Arora

Abstract: A series of cinnamic acid derivatives (TA1–TA12) were synthesized and tested for their in vitro antibacterial activity against different strains of bacteria. Ampicillin anitibiotic is taken as standard for antibacterial activity. This study found that out of 12 synthesized compounds 6 compounds namely TA1, TA4, TA5, TA7, TA8, TA11 showed good activity against different microorganism strains as compared to standard drug. Amongst the six compounds, it is further found that compounds TA5, TA8 and TA11 having 4-hydroxy group in their structure showed best antibacterial activity as compared to standard.

Pages: 643-647  |  552 Views  18 Downloads

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How to cite this article:
Amrita Parle, Tejpal Arora. Synthesis and antibacterial screening of some novel cinnamic acid derivatives. Int J Chem Stud 2017;5(3):643-647.
International Journal of Chemical Studies