Vol. 5, Issue 2 (2017)

Benzimidazole derivatives play important role in medical field with so many Pharmacological activities such as antimicrobial, antiviral, antidiabetic and anticancer activity. The potency of these clinically useful drugs in treatment of microbial infections and other activities encouraged the development of some more potent and significant compounds. Benzimidazoles are remarkably effective compounds, extensive biochemical and pharmacological studies have confirmed that these molecules are effective against various strains of microorganisms.

Due to their enormous medicinal value, the research and development of benzimidazole-containing drugs is an increasingly active and attractive topic of medicinal chemistry. This review enlightens about the chemistry of different derivatives of substituted benzimidazoles along with their pharmacological activities.

Furthermore, the present review also provides the recent advances in the development of benzimidazole-based drugs along with new perspectives. We hope that this paper will open up new opportunities for researchers to design future generation novel and potent benzimidazole containing drugs.