International Journal of Chemical Studies
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P-ISSN: 2349-8528, E-ISSN: 2321-4902   |   Impact Factor: GIF: 0.565 NAAS Rating: 5.31 NEW

International Journal of Chemical Studies

Vol. 5, Issue 2 (2017)
One Pot three component organocatalyzed synthesis of octahydroquinazolinones


Author(s): Bhupal Singh Karki, Shivani Verma, Akansha Agrwal and Virendra Kasana

Abstract: Efficient one pot three component synthesis of octahydroquinazolinone derivatives by reacting substituted aromatic aldehyde, 1,3-dicyclohexanedione, urea/thiourea at room temperature catalyzed by L-proline as an ecofriendly catalyst with excellent yield (70-95%) and short reaction time is reported. The structures of synthesized derivatives were characterized and confirmed by FT-IR and 1HNMR data.

Pages: 280-290  |  604 Views  26 Downloads

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How to cite this article:
Bhupal Singh Karki, Shivani Verma, Akansha Agrwal, Virendra Kasana. One Pot three component organocatalyzed synthesis of octahydroquinazolinones. Int J Chem Stud 2017;5(2):280-290.
International Journal of Chemical Studies