International Journal of Chemical Studies
Vol. 4, Issue 2 (2016)
Synthesis and characterization of transition metal ion (Coii, Niii, Cuii& Znii) complexes of Schiff bases derived from aminothiazole and their biological activity
Author(s): BN Muthal, BN Raut, AS Tekale
Abstract: A series of Schiff bases have been synthesized by reacting 4(p-fluro phenyl) 2-aminothiazole and R-substituted Salicylaldehyde (R-H, 5-Me, 5-cl and 5-ome and 2-hydroxy-1-naphthalene. The bases and their metal complexes were characterized by elemental analysis, UV-visible and Infra-red spectra, magnetic susceptibility and conductivity measurement. The Schiff base complexes act as monomeric and have octahedral in geometry. The ligand coordinated through oxygen atom of phenolic –OH group and the nitrogen atom of azomethine group. The complexes are non-electrolitic in nature.rnThe stability constants and thermodynamic parameters (ΔH,ΔG&ΔS) were recorded. The –ve ΔG in each cases indicates the complexation is spontaneous. The enthalpy change is exothermic. The positive value of ΔS indicates the reactions are entropically favoured.rnThe Schiff bases and their metal complexes were screened for antibacterial, antifugal and pesticidal activity.
Pages: 78-82 | 1112 Views 37 Downloads
How to cite this article:
BN Muthal, BN Raut, AS Tekale. Synthesis and characterization of transition metal ion (Coii, Niii, Cuii& Znii) complexes of Schiff bases derived from aminothiazole and their biological activity. Int J Chem Stud 2016;4(2):78-82.