International Journal of Chemical Studies
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P-ISSN: 2349-8528, E-ISSN: 2321-4902   |   Impact Factor: GIF: 0.565 NAAS Rating: 5.31 NEW

International Journal of Chemical Studies

Vol. 4, Issue 2 (2016)
Synthesis and anti-bacterial, anti-fungal activity of novel pyrazoline derivatives containing phenothiazine ring


Author(s): V Prabhakar, K Sudhakar Babu, LK Ravindranath, P Guru Pratap Reddy, J Latha

Abstract: A Novel Series of Compounds were synthesised by Condensation reaction of phenothiazine aldehyde with Substituted Acetophenone derivatives 4 (a-d) in presence of alcoholic Sodium hydroxide Solution to get Chalcone Intermediates 5 (a-d), which were further treated Hydrazine hydrate in Ethanol to get Novel Pyrazoline Derivatives 6 (a-g). The Structures of new compounds were confirmed by IR and 1H NMR and 13C NMR Spectral Data. When these compounds were evaluated for Anti-bacterial and Anti-Fungal Activity, Some of them were found to possess Significant Activity, When Compared to Standard Drugs.

Pages: 51-58  |  1016 Views  42 Downloads

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How to cite this article:
V Prabhakar, K Sudhakar Babu, LK Ravindranath, P Guru Pratap Reddy, J Latha. Synthesis and anti-bacterial, anti-fungal activity of novel pyrazoline derivatives containing phenothiazine ring. Int J Chem Stud 2016;4(2):51-58.
International Journal of Chemical Studies