Vol. 4, Issue 1 (2016)
Synthesis and biological evaluation of (E)-S-1H-benzo[d]imidazol-2-yl 2-benzylidene)hydrazinyl) ethanethioate derivatives
Author(s): Vikas A. Desai, Darpan B. Patel, Jitesh B. Patel
Abstract: We have developed a highly efficient approach for the preparation of S-1H-benzo[d]imidazol-2-yl 2-hydrazinylethanethioate 4 in acetic acid. Product 4 was further used for the synthesis of (E)-S-1H-benzo[d]imidazol-2-yl 2-substituted benzylidene)hydrazinyl) ethanethioate derivatives 6a-k under mild reaction condition. The synthesized compounds were further confirmed by IR, 1H NMR, 13C NMR and mass spectroscopy. All the synthesized compounds were screened for their biological activity against different strains of bacteria, fungi and antitubercular.
Pages: 54-60 | 1944 Views 152 Downloads
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How to cite this article:
Vikas A. Desai, Darpan B. Patel, Jitesh B. Patel. Synthesis and biological evaluation of (E)-S-1H-benzo[d]imidazol-2-yl 2-benzylidene)hydrazinyl) ethanethioate derivatives. Int J Chem Stud 2016;4(1):54-60.
