International Journal of Chemical Studies
Vol. 3, Issue 4 (2015)
Interaction of biologicallyactive metal ions with cytidine 5'-triphosphate and nicotinic acid
Author(s): Rajendra Kumar, Brajesh Kumar Shukla, Shalini Verma, V Krishna
Abstract: Equilibrium study on the mixed ligand complex formation of Cu (II), Cd(II) withCytidine 5'-triphosphate and Nicotinic acid, under experimental conditions (constant ionic strength I =0.1 mol/dm3, at 37±0.10C) and potentiometric pH titrations were carried out to determine the stabilities of the binary (1:1) and ternary (1:1:1) complexes, with M(II)= Cu(II), Cd(II) bivalent metal ions, where the self-association of the cytidine 5'-triphosphates (CTP) is negligible. The percentage of species distribution curves have been demonstrated with the help of ORIGIN 6.1 software. Stability constant have been determined through the method suggested by Irving & Rossetti and further refined through Stability Constant of Generalized Species (SCOGS) computer program. Species distribution curves of complexes have been plotted as a function of pH.The mixed ligand (1:1:1) ternary complexes were occurred simultaneously in most cases generally at high pH with gradually declination of binary complexes of particular metal complexes.
Pages: 20-23 | 1185 Views 11 Downloads
How to cite this article:
Rajendra Kumar, Brajesh Kumar Shukla, Shalini Verma, V Krishna. Interaction of biologicallyactive metal ions with cytidine 5'-triphosphate and nicotinic acid. Int J Chem Stud 2015;3(4):20-23.