International Journal of Chemical Studies
Vol. 3, Issue 3 (2015)
1, 5-Benzodiazepines: A Review Update
Author(s): Ofentse Mazimba, Tracy CS Molefe
Abstract: 1,5-benzodiazepines are the most studied group of diazepines, which are a class of drugs prescribed against psychotic disorders. An immense literature is continually produced from the research work carried out about the synthesis and pharmacological activities of 1,5-benzodiazepine, two recent reviews in 2013 outlined the importance of this privileged pharmacophore. Due to their wide range of biological properties the benzodiazepine nucleus has continued to attract many investigators to synthesize and screen their analogues for all possible activities. This current review article describes the literature relating to 1,5-benzodiazepines synthetic strategies and provides highlights of the different pharmacological activities accomplished since 2013.
Pages: 46-52 | 1022 Views 16 Downloads
How to cite this article:
Ofentse Mazimba, Tracy CS Molefe. 1, 5-Benzodiazepines: A Review Update. Int J Chem Stud 2015;3(3):46-52.