International Journal of Chemical Studies
Vol. 1, Issue 4 (2013)
Synthesis, Structural Characterization And Biological Activity Of Transition Metal Complexes Of Schiff Base Ligand – Furan Derivatives
Author(s): Mohd. Asif Khan, Ruchi Agarwal, Shamim Ahmad
Abstract: A series of Ti (III), Mn (III), V (III), Fe (III), Co (III), Ru (III), Ru (II), Vo (IV) and Cu (II) complexes have been synthesized from the Schiff base ligand. The Schiff base ligand is derived from 2-furancarboxaldehyde and O-phenylenediamine. The resulting complexes were characterized by elemental analyses, magnetic moment measurement, molar conductance, thermal analyses (TGA), IR, 1H-NMR and solid reflectance. The ligand dissociation, as well as metal ligand stability constants were calculated, pH-metrically at 25 0C and ionic strength m = 0.1 (IM Nacl). IR spectra show that ligand is coordinated to the metal ions in a tetradenatate manner, with ONNO donor sites of azomethine N and furan O. The molar conductance data reveals that all metal chelates are electrolytes. The electronic spectral data of the complexes displayed the proper transitions and octahedral geometry. The synthesized ligands in comparison to their metal complexes, were also screened for their antibacterial activity against bacterial species, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus pyogenes. The activity data show the metal complexes to be more potent antibacterials than Schiff base ligand against one or more bacterial species.
Pages: 55-63 | 1094 Views 22 Downloads
How to cite this article:
Mohd. Asif Khan, Ruchi Agarwal, Shamim Ahmad. Synthesis, Structural Characterization And Biological Activity Of Transition Metal Complexes Of Schiff Base Ligand – Furan Derivatives. Int J Chem Stud 2013;1(4):55-63.