Vol. 1, Issue 4 (2013)
Synthesis and characterization of pyrimidine bearing 1, 3, 4-oxadiazole derivatives and their potential antifungal action
Author(s): Andrews B*, Mansur Ahmed
Abstract: A series of pyrimidine bearing 1, 3, 4-oxadiazole derivatives have been synthesized and evaluated for antifungal activity. All the structures of the newly synthesized compounds have been supported by IR, 1H-NMR, 13C-NMR, GC-MS and CHN analysis. Most of the compounds have shown promising antifungal activity when compared with the standard drug amphotericin-B.
Fig. 1: 5-(5-amino-1,3,4-oxadiazol-2-yl)-3,4-dihydro-6- methyl-4-phenylpyrimidin-2(1H )-one 3a.
Pages: 32-39 | 2204 Views 162 Downloads
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How to cite this article:
Andrews B*, Mansur Ahmed. Synthesis and characterization of pyrimidine bearing 1, 3, 4-oxadiazole derivatives and their potential antifungal action. Int J Chem Stud 2013;1(4):32-39.
