International Journal of Chemical Studies
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P-ISSN: 2349-8528, E-ISSN: 2321-4902   |   Impact Factor: GIF: 0.565

Vol. 1, Issue 3 (2013)

Synthesis, Antitubercular Activity of Novel Quinoxaline Derivatives


Author(s): N.Ramalakshmi*, Rahul Sidhayae, S.Arunkumar, C.N.Nalini

Abstract: Quinoxaline derivatives were synthesized and evaluated for antitubercular studies. All the synthesized compounds exhibited an interesting activity profile against the strain. The results revealed that the activity is considerably affected by various substituents. The compounds with quinolone substitution exhibited better antitubercular activity. The compounds 2c, 2d and 2e and 2i, 2j and 2k with ciprofloxacin, norfloxacin and sparfloxacin with sulphonamide and isoniazid substitution exhibited good percentage inhibition.

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Pages: 20-27  |  1793 Views  118 Downloads

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How to cite this article:
N.Ramalakshmi*, Rahul Sidhayae, S.Arunkumar, C.N.Nalini. Synthesis, Antitubercular Activity of Novel Quinoxaline Derivatives. Int J Chem Stud 2013;1(3):20-27.
 

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