International Journal of Chemical Studies
  • Printed Journal
  • Indexed Journal
  • Refereed Journal
  • Peer Reviewed Journal
P-ISSN: 2349-8528, E-ISSN: 2321-4902   |   Impact Factor: GIF: 0.565

Vol. 8, Issue 4 (2020)

Synthesis and antiviral activity of 1-(n-substituted amino acetyl)-2-(5-substituted phthalimidomethyl) benzimidazoles


Author(s): Dr. Archana Jyoti

Abstract: Phthalic anhydride and 3-Nitro Phthalic anhydride were reacted with 2-aminomethyl benzimidazole in pyridine to give 2- (5-substituted phthalimidomethyl) bezimidazoles. These benzimidazoles were refluxed with chloroacetyl chloride in dry benzene followed by reaction with different secondary amines to give 1-(N-substituted amino acetyl)-2-(5-substituted phthalimidomethyl) benzimidazoles. Antiviral activity of these compounds was studied against Ranikhet Disease Virus (RDV) and Vaccinia Virus (VV). Some of these compounds have been found to be active against RDV.

DOI: 10.22271/chemi.2020.v8.i4a.10151

Pages: 14-16  |  1198 Views  161 Downloads

download (4988KB)

International Journal of Chemical Studies International Journal of Chemical Studies
How to cite this article:
Dr. Archana Jyoti. Synthesis and antiviral activity of 1-(n-substituted amino acetyl)-2-(5-substituted phthalimidomethyl) benzimidazoles. Int J Chem Stud 2020;8(4):14-16. DOI: 10.22271/chemi.2020.v8.i4a.10151
Important Publications Links
International Journal of Chemical Studies

International Journal of Chemical Studies

 

Call for book chapter
International Journal of Chemical Studies